If you want to save the hide then 223 with 40 gr Nosler Ballistic Tip, they generally do not come out but they do make a mess of everything inside. I have taken them out to 300 yds with this combo.

If you don't care about the hide then 22/250 with the 50 gr Nosler Ballistic Tip. The 22/250 is a "reach out an touch them machine" for the long shots. I have taken them out to 500 yds with this combo.

drover

223 Rem, my favorite cartridge - you can't argue with truckloads of dead PD's and gophers.

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