The first chamberings that come to mind are the .270win and the 7mm-08, but a well-loaded 150gr bullet in a .308 is actually right there with them. Any one of the three gets my vote for "best". The .308 is about like a plain old manual-shift Honda Foreman. It'll always get it done, even though it's nothing fancy, and nobody can honestly tell you it's not a solid pick, even if it's not sexy.
