By his reasoning, the JNJ vac is somewhat similar to a flu vaccine, it's 'build' or 'footprint' has been around for a while.
Like the Pfizer and Moderna shots, the Johnson & Johnson shot is based on the virus's genetic instructions for building the spike protein. But unlike the Pfizer and Moderna shots...which store the instructions in RNA...the Johnson & Johnson shot stores the instructions in DNA. The modified adenovirus enters the cell and travels to the nucleus where it injects this DNA. Antigen transcription...
where it’s read and copied into messenger RNA...takes place in the nucleus and then nuclear export occurs,
via that messenger RNA, and travels to the cell cytoplasm where’s it’s then translated into spike protein synthesis. Those spike proteins then travel to the cell surface where they are recognized by the immune system.
