I bought new #1Vs in .223 and .22-250 about thirty-five (or more) years ago. Both were very accurate, but neither would hold a zero for long, and, as I recall, I tried different scopes.

Since then, I worked with another .22-250, a bolt-action. It had a commercial Mauser action and a Lilja barrel and a 6X Lyman silhouette scope. Very accurate with many bullets but I generally used the 50 grain Sierra Blitz and H4895 powder. I don't remember whether or not I tried this combination in the #1V, but I suspect it would have been accurate in it, too.