A little different slant on loading for a 22-250.
I developed my favorite load for the 22-250 in '79 for a 14 inch twist MIJ Wea Mk V Varmintmaster. Fifteen years later, the load worked just as well in a new Savage 112V, until I toasted the barrel.
34.3 gr IMR 3031 with a CCI 200 and the Hornady 60 gr spire point gave very consistent .75 moa.
Not the fastest or flattest load over the first 250 yds. But I developed the load to shoot beyond 300 yds.
Final note: The Hornady flat base spire point always shot well for me in 14 twist. Not so with any boat tail poly tip in 60 gr.
