If you cant find Sierra or Nosler, Hornady seems to be pumping out product. Their #2240 the 50gr. SX shot very well for me in a 77V over 4895 or RL15 with devastating ('splodey) results on groundhogs. Pushed not quite to max, I think it was around 3800fps, 300 yds shouldn't be much of a problem. I've heard Varget may do better, but it wasn't a thing yet when I had a 22-250.
