The 10 is quite simply the best, most useful true auto pistol cartridge in a reasonable-sized package, that we have had in my lifetime. I've owned at least a half-dozen examples over the years. I currently don't have one because it is a dead duck and there are other fine cartridges that are better choices.

For strictly performance purposes, I don't think you can beat the 10. The problem is availability. The 45 Auto +P is almost equivalent as far as shooting critters. The 40 S&W and 45 Auto are both roughly equivalent in one-shot manstopping. The 9 is not far off. All three of the latter cartridges are available in more concealable packages. All three are more popular and are available at any Wal Mart near me. So there are cartridges that are cheaper and more readily available in a wider variety of delivery systems than the 10. That's why I don't have one anymore.