Lots of comments from lots of folks. Bet quite a few of them have never shoot a moose before either. I have been moose hunting, but only got to help with the quartering. I have however owned and shot several of the mentioned calibers. Biggest animal was a caribou, with a 6.5X55. Don't really remember all of the deer, used everthing from an 9.3X62 to a 243. All of them killed the animals dead with good shot placement. Given the choices mentioned I'll still say the 6.5X55 with 120 to 140g bullets is a better choice for moose.