My Bob a Ruger MKII with some tweeks done to it kilt lots of deer, mostly from other family members Muleys and whitetails both. Along with yotes and other ground burrowing and flying vermin.
My 14 year old shoots it well. She killed here first whitetail off of my shoulder last year at 120 some yards. It was a "DRT" deal.
The wife smoked her first muley buck with it at around 200 yards. Dropped, flopped around till outa site. Found it very dead not feet from where it had been shot, just flopped into a low spot.
As for a sole deer cartridge, I would not hesitate to use the Bob.... I just get lured away by louder, harder kicking rifles
The loads that did good on deer were 100 partition nudging 3100 fps and 117 grain btsp hornady at 2900 fps. Both shot easy 1/2 inch groups at 100 yds.
Got a hold of some OLD school partitions, in 117gr. simi-spitzers. Now them puppies leave holes in deer and shoot beautifully. To bad I only have less than 50
