I too started with a 30-06 for my first riffle.
Then I moved up to a BBR 338 mag in 1984 for larger big game
Shot many loads from 225 -275grains and settled on the 250 grain

If I could pick again it I would go bigger ..... 375 H&H mag. using 270 grain

Maybe I am loony, its just that this last moose season, every road or cut line I was on had a Grizz tracks on it and he was Big !