I've got a 2000 4runner with 187,000 on the clock. No mechanical issues at all so far. With the V-6 3.4 liter it is a tad underpowered at times when we pull the two place atv trailer.

I had a 95 3.0 liter 4wd PU and had the head gasket issue at 237,000 miles. I 'fixed' it with a can of nano technology head gasket repair. It fixed the gasket but I had to replace the radiator. The guy I sold it to is still driving it with the same motor.