If you get the opportunity to try long range sixgunning, it'll open your eyes.

On a deer hunt several years back we were in a cabin on one side of a bay with the other side approximately 400yds distant. [Linked Image]

I'd brought a box of plinking ammo for my 480 and would plink across the bay in the evenings. After I figured out the drop I was hitting a rusted out 55 gal drum.

I've seen a shooting buddy place all five shots from an FA 475 linebaugh on a 200 yd ram sillouette, and he was shooting offhand.

If you'd consider a 45 acp to have sufficient power to kill a deer within 50 yds, a 44 mag with a 240 gr cast bullet has the same power at 300yds, and the heavier cast bullets are better yet for extended ranges.

The way I look at it, you can never be too good of a shot. Practicing at extended ranges helps you at every range.