Certainly not the level of experience as some posters but my direct experience is.
> 30-06 with a 180 Gr. NPT @ approx. 80 yards away.
> 35 Whelen with a 250 Gr. Speer Spitzer a touch less than a 100 yards away.
> 338 Win. Mag with a 250 Gr. NPT about a 125 yards across a bog.
All of them took a moment to realize that they were next heading to the freezer, none went more than 25 yards before falling over.
Then the fun started, there is a lot of moose on a moose.

Over the years my family and friends have used a 270 WCF, 308 WCF, 30-06, 7mm Rem. Mag, 300 Win. Mag, 303 Brit., 348 WCF, 30-40 Krag, 35 Whelen , 404 Jeffery and a 375 H&H for moose and nothing required more than two shots; almost all of them used factory ammunition with no ill effects.

StarchedCover


Semper Fi