this is what I've killed moose with, to date:
.308 win 180 NP ( 4 moose)
.308 win 165 Rem CL (1)
.356 Win 220 Speer FP ( 1)
.35 Whelen 250 Speer GS ( 1)
.375 H&H 300 Fed RN ( 1)
7x57 175 Norma RN (1)
Each worked as well as the other, I'd choose the rifle I liked rather than the cartridge within this list. If really serious about the cartridge with maximum advantage I might pick my .35 Whelen because I have taken more than a dozen elk with it and like it a lot. It penetrates through heavy shoulder bones a bit better than all on the list except the .375 if such a shot ever becomes necessary.

Last edited by castnblast; 01/30/18.