I also agree with Calvin on the rifle/ballistic side of the equation. Part of the deal is to match your gear to conditions and that includes your rifle. Most cartridges are capable. But what if you only hunt in the timber, shots are less than 100 yards, and shots may be hard quartering? I prefer not to have a thin skinned bullet capable of expanding at 6-7-800 yards. Conversely if your hunting is spot/stalk or meadows and shots be extended with time to let an animal position for a broadside shot, a higher BC bullet is likely a better choice.
Same goes with rifles. I tend to carry something shortish for my timber hunting and 24" barreled for my meadow hunts. Bullets matching both situations.
