My .257 Roberts Ruger MII shoots well with quite a few different bullet/ powder combinations. I settled on 110 Nosler AB with 42.5 grains of H4350. Leaving some velocity on the table at 2800FPS, deer have yet to notice the lack of speed. The last buck was a pain to track. Had to go at least 20 yards before I found him. The Nosler AB do like to be seated a wee bit deeper tho.
