With a 180gr in 7mm or a 212gr in .308 Berger, would you take a frontal chest shot OR a quartering away, last rib shot to hit the offset shoulder on a bull?

I have only shot elk with NABs, NPTs, Swift Scirs, and Barenss TTSXs. I would with those but have always wondered if I should with Bergers.

I have a 7mm RM that absolutely loves 180gr Hybrids and I have only used them on deer but the initial question has always made me question it, so what say you, Berger guys? For a classic broadside shot, no problem, but with a tough angle, would you under typical situations, all things considered?