"I agree that shot placement is king, buts its not the whole story.
Shoot a elk with a 22 mag behind the shoulder and it will be dead on its feet. It also might run a mile or more with little to now blood. Now do the same with a 300 win mag with a decent bullet and it might drop in its tracks or make a short run bleeding profusely in the process.."
With a .22 mag, a shot behind the shoulder would not be proper placement IMHO. I'd aim for where the spine meets the skull.
Bill Quimby
