Mark, I use turrets but where I live not on big game.
And when I do hunt out west the majority of my hunting is archery....anyway this last year I was in AZ with my AR-15 (grim reaper) and was twisting turrets on jackrabbits.
Closest shot was 80 yds and longest was 729-749.....cant remember which, but I did miss the rabbit....by 10 inches.
My farthest kill was 580 and I averaged around 420.....anyway it wasnt big game but I was still twisting turrets.
This year if I dont get drawn for my Kaibab hunts I will buy a leftover Coues tag and hunt with Firstcoueswas80 with Carnivore and she wears turrets.
Also when I go to AZ in December I will be taking my 243 AI and it will also be wearing turrets.
I am a big proponent of them.