I have settled on a couple of bullets for the .375 H&H and that would apply to the 375 Ruger also..

My favorite soft for DG is by far is the wonderful 350 gr. Woodleigh. and its a great bullet for anything that doesn't require a solid..

If, however, I was restricted to one bullet for all of Africa it would be the GS Customs "Cup Point"..Diker to Hippo, Buffalo, Lion it would suit me just fine. If elephant were on the menu then I'd probably opt for the GS Customs flat point solid, but I believe the cup points would get the job done..I just don't like being limited in bullet choice..

For the USA, about any good 300 gr. soft suits me. The Nosler rates high as do the lighter GS Customs HV HPs, and the 350 gr. Woodleigh still fits in well for elk in the thick stuff.