Have had the pleasure of taking deer with many different bullets over the years:

.50 cal, 385 gr soft-swaged Hornady Great Plains, from a traditional muzzle loader

.458" 405 gr Rem FNSP from a .45/70 Marlin

Couple of different .44 mag JHP/JSP loads from a revolver

230 gr JHP bullets from a .45 ACP 1911

Quite a few different smaller bullets, 6mm - .30 cal, some "premium" some not. I'd say the Nosler Ballistic Tip is real favorite for both accuracy and lethality, even in the little 95 gr version. Have to say that I'm a real fan of the milder cartridges, 6mm - .30 cal, particularly the 6mm Rem, .25-06 and the .308 Win. No muss, no fuss, just pleasant to shoot, tag-filling rifles.

Shot a few with a 55 gr .223 as well.

Can't think of any that got away or even ran very far. I think it's a lot more about hitting them right, than what they're hit with.

Guy