I'm not an Alaska guy but for central and northern BC I would go with the 338wm. Plenty of penetration, lots of range, it's all good.

I shot 275grn SAF's for awhile but settled on the 250grn SAF's as my practice bullets are all 250grn. I can't see 25 grains of bullet weight making that much difference at impact, nothing wrong with the bullet -worked darn well.

I'm with Kute's on one load. I'm not skilled enough to be good at all the ranges I shoot at with multiple bullet weights and loads so I just shoot 250's.

Mr Shoemaker, I am intrigued by that scope on your daughters rifle. I am assuming it is holding up well? Decent at lower light levels?