I will use both as required. Given a choice, I will take my Ithaca Deerslayer.
For serious deer hunting the rifled barrel, a scout scope and Winchester or Hornady Sabots is usable to 200 yards.
For does in rangeland with some draws a smoothbore Deerslayer barrel with a 2.5X Scout scope works for deer to 100 yards and pheasant inside 30 yards. 12 or 20 gauge works just fine. Ditto if I have filled my tag and am not allowed to hunt with a CF rifle larger than .224 cal.
This isn't the best state for Muzzle loaders. The rain makes it tough.