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Son-in-law shot an antelope with a 168g A-MAX from a .30-06. The bullet shredded much of the left backstrap and ham. It put the animal on the ground but needlessly ruined a lot of meat.

Just goes to show the obvious - the heavier the bullet the less construction matters. I've often stated I believe most of the game I've shot could have been taken with my .22-250 and a 40g BT. At the same time, when deep penetration was needed the .22-250/40g BT isn't the combination I would have wanted in my hands.