I've killed a few bulls. I aim for tight behind the shoulder, 1/3 up from the bottom of the chest. I avoid the shoulder knuckle. They don't go far and I don't have the nightmare of bloodshot and bone fragments all through the shoulders and into the rib meat.
Two years ago I broke the left scapula right along the ridge with a 140 Partition from a 7mm-08. The bullet lodged under the hide on the opposite side. Very little mess and DRT.
This year's bull with the same combo I hit behind the shoulder, the bullet exited, still DRT. Hardly any mess at all.
P