[img]https://wildcountryphotos.files.wordpress.com/2016/02/elk-anatomy-with-arrows.jpg?w=490[/img]

Maybe pictures will help.

If you put a bullet into the area shown on the circulatory system, that elk will not go far. If you get the aorta as it comes out of the top of the heart you get DRT. No blood pressure to run anything.

If you try for the shoulder joint where the dense heavy ball at the end of the humerus is you need a very heavy bullet to get through from one side to and through the other. Doing that you get a front lung hit, at least with bone fragments and a pass through with the bullet. Deadly, but messes up a lot of meat. Have done that once with .338 mag and 250 gr Swift A-Frame. Not a shot I would prefer to take but for the circumstances at the time. He still kind of half jumped anyway, but both shoulders collapsed. Had he been on the edge of a cliff, he might have made enough movement to go off the edge. Would not have made it over a fence, though.