For the last 15 years, I've carried a P226 in my flight vest with two mags, and I've felt very comfortable with it. If I ever have to use it, I've had to ditch the aircraft somewhere bad, and I like the capacity of the 9mm in that situation.
Personally, I find a Glock 17 in .357 SIG to be about the best combo available (one lives in my nightstand), but you couldn't teach 75% of active duty personnel to shoot that cartridge well.