So, after all the drama thus far, answer me this: If I wanted to carry my .45 Colt New Service (somewhat marginally more strong than a Colt SAA), loaded with fairly stiff 255 grain semi-wadcutter handloads, out to distances at which I can consistently hit a softball sized target (say 30 yards)- would I be kidding myself? Note that I am not a pistolero, just a guy who dabbles with a couple Colts and who happens to be pretty good with this old New Service.
You'll kill deer just fine, buddy. Put the bullet in the boiler room, and make sure the knife is sharp.