There are some big 250lb+ whitetail deer in PA in the thick woods. Lots of guys use a 30-06 or heavier in the belief that they need to need to put them down fast. In Potter County for example, on opening day, if a hit deer runs 40 or 50 yards, someone else is going to put lead in it, then try to claim it. JD Jones wrote an interesting article that he sold a lot of 45-70 Contender (pistol) barrels to PA hunters who wanted to put down deer fast, with out them running far. Whether you think bigger calibers put down big whitetail deer faster, is a matter of opinion. Plenty of people do believe it though, and they surely practice it--right or wrong.
I've been hearing tales of 250 lb PA deer all my life. Next one I see will be my first.
I have seen one that went 190# dressed. It was a good 4.5 year old, 150" typical. Won Crawford County that year...big ole boy...
