I've been killing most of my deer with cast bullets in .30 rifles and/or soft lead balls out of muzzle loaders. Old technology works today as it has for over half a millennia. It's a deer, not a truck. There are many more things in life to worry about than deer bullet efficiency- putting the bullet where it counts being chief among them.
I got some 130 TSX's with a mind to try them in a .300 Savage. Been two years now, maybe some day.