I've epoxied-on bases (and the screws that hold them to the receiver) for over 20 years on every rifle I own. You end up with a "monolithic" mount.
I use JB Weld as it's a farily "weak" epoxy. Apply it thinly and evenly across the base bottoms, and a small dab on the end of the screws. Tighten down slowly, alternating between screws. Take up to 5+ minutes to tighten allowing excess epoxy to squeeze out.
Clean up with acetone and/or denatured alcohol and qtips, cotton swabs and paper towels.
To remove bases, take barrelled action out of the stock and lightly kiss the bases with a Benzomatic torch until screws loosen.