I'm getting too old for a grizzly hunt, I suppose. I think though I'd be carrying my 375 Whelen AI on a Mauser 98 action if I were to go. I sold my last 338. I might (probably not) take my pre-64 375 H&H AI.
But I recall the killing of the polar bear with a 22 LR was by a native gal - Eskimo if you will, not an interior grizzly bear.
This is a link to the actual story about the World Record grizzly bear being shot by an elderly Native woman, with a 22lr.
I can find nothing about a verified polar bear kill using a 22lr, just a number of internet claims without names. I have zero doubt it can be done. I killed my first moose with one more than 50 years ago. I just cannot find a valid report of a polar bear kill.
Mark Begich, Joaquin Jackson, and Heller resistance... Three huge reasons to worry about the NRA.
