Leopards are not difficult to kill with proper shot placement and a decent bullet. That said, the two I’ve shot were with a 300 Winchester and 180 grain Nosler Partition and a 338 Winchester with 225 grain Trophy Bonded Bearclaw. Both died quickly. I’ll be leopard hunting later this year and shooting my 338, with a 225 grain bullet, either a Nosler Partition or Barnes TTSX. Either will do fine.
If I were hunting only leopard, I’d probably shoot either a 270 or 30-06 with a partition or accubond.
