I have a 300 H&H that shoots 180gr TTSX's into tiny groups, thinking that would work just fine. Of course, any my 270's shooting 130gr mono's or 6.5x55 with 129gr IL's would work.
I could also go big with my 375 H&H and 270gr TSX's or 416 Remington shooting 350gr TSX's.
Love having choices.....