If you are shooting a .458 bore, I found the 300 grain Nosler Partition to be very effective. at a MV of 2200 fps.
[Linked Image from jpgbox.com]

CRS, NRA Benefactor Life Member, Whittington Center, TSRA, DWWC, DRSS
Android Reloading Ballistics App at http://www.xplat.net/