Jorge,
Have seen one leopard lost when the shot was a LITTLE too far forward with a .300 Winchester Magnum and a good180-grain bullet at over 3100 fps. I know this because I was there, and helped follow it up. It fell out of the tree with a thump that made it sound very dead, but by the time we approached the blind there was only some blood and a little shoulder-
bone. We followed the blood trail for over an hour, in the dark, and while the leopard's eyes showed a couple of times in the flashlights, the blood-drops eventually ended. SEVERAL hunters went back the next morning, with trackers, and never found it.
From what several experienced PHs have told me, it's actually better to hit a leopard a little farther back than too far forward--which is true of many cats.
