Originally Posted by MikeReilly
I wonder how a non-sterilising vaccine like rotavirus vaccine works so well in a population in which the virus has been endemic...

Kinda disproves your point.

"Although vaccine efficacy ranges from 84–98% in high-income settings, it is below 60% in many resource-poor settings where the majority of deaths due to rotavirus-associated disease occurs [8–12]."

"Why do we need to continue research on rotaviruses? The diminished vaccine efficacy in resource-poor countries and the exclusion of certain patients from rotavirus vaccination highlights a need for improvements to vaccine design. In order to make the most rational improvements possible, there must be a more thorough knowledge base surrounding the innate and adaptive immune response to rotavirus, the viral targets that could be modified to improve vaccines, and the mechanisms underlying how targetable viral proteins function. Vaccine effectiveness must also be continually monitored to determine if commonly circulating strains of rotavirus will change over time, or if a newly pathogenic rotavirus emerges through natural variation."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967271/

Tell me more about how this non-sterilizing rotavirus vaccine "works so well"..........

Kinda disproves "your" LIE.

Oh, and you still don't even know how to spell non-sterilizing.

Also, the topic is Corona virus, not your strawman argument you just used, rotavirus.


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