I guess I was taking the OP's "real world" scenario into consideration:
24" barrel
Factory ammo
Years ago, I built a .257 Weatherby with a 26" tube because I rationalized the only reason to own one (over the 25.06) was really standing on the gas with a 100gr. mono.
I rationalize the same for the .270 Weatherby.
Go big/long or go home.