You gotta be 100% set-up on both ends.

Air fare is cheap and quick compared to driving.
I go back and forth often, at times just for the weekend.

I can go to Montana from Florida in about 7 hours if I catch the right flights, I pickup a couple hours doing it.
Breakfast in Florida, dinner in Montana, snow machining the next morning.
Got my water setup to where I can dump the lines in the time it takes to have a cup of coffee and then outta there.