45 of Varget was my go to load with 139/140s in partial sized brass, quite warm, safe IME and my rifles. That said a few grains less and a bit less speed would not change the outcome on an animal IMHO. I found the same charge of IMR4064 gave a tad better accuracy, than Varget...and Varget has given me some great results. No doubt, BG is a fave by many.