Loading seems to matter more than cartridge.
I'm loading down 223, 22-250, 6mmBR, 243, 6Creedmoor, 6.5x284 7x57, and most recently 7.62x39. I haven't gotten to the 308s and above yet.
The local whitetail don't know the difference.
Post your question in the reloading forum below for some specifics!