My two choices at this point in life, are :
The 6.5 Grendal Predator I have, with aftermarket polymer mags
The second would be the 6 x 45 with a one in 7 twist, with a 20 inch Predator sized barrel, on a Savage Axxis 2 action.
I used both the last couple of seasons.. They don't use a lot of powder, yet are definitely capable at 250 yds and under, as well as any other rifles I own, in any other caliber I have used also.
But 30 grains of 4198, will make about any cartridge capable for low recoil and deer medicine to 300 yrds.