I’ve used the 250, 243, 22-250 and 223 a lot for deer sized game. The .223 is just as effective as the others and has several advantages of its own. Brass is everywhere, 25 grs of powder per shot, small rifle primers abound, quietest of the rounds you suggested, lightest recoil of all, and super easy to work up accurate loads for. It’s easily my favorite cartridge and simply a classic little cartridge.


Will Munny: It's a hell of a thing, killing a man. Take away all he's got and all he's ever gonna have.

The Schofield Kid: Yeah, well, I guess they had it coming.

Will Munny: We all got it coming, kid.