Dwayne,
The regular 250, even loaded to nearly 3000 fps with 100 grain bullets, does seem to have a milder report than similarly loaded 243s I've been around. I suppose the combustion products of 35 grains of H4895 coming out of a 25 cal hole make a smaller ruckus than those from 41 grains of 4350 out of a 24 cal hole.
My best to you and yours,
m
So load a 243 with 35 grains of H 4895 and a 100 grain bullet....then all you are giving up is 1/100th an inch of bullet diameter.