Other than you are a one gun man with a bigger caliber, why would you ever feel the need to use anything bigger than a .243 Win for whitetail?
Ain't no "need" for anything bigger. I have used rifles from .223 to .375H&H to kill KY WT Deer. The .243 with a 95gr NPT kills 'em just as dead as the others... Mostly one shot, DRT's, to boot...
