Between me and my son we've killed several deer with a 243 using 100gr Rem Corelokts. We never lost one and the ones that ran went a shorter distance than with a larger caliber cartridge. He shot one doe at over 200 yards and she was DRT. I never recovered a 243 bullet but my son did recover two. One was a head on shot and the bullet was in the paunch and the other was through both shoulders and just under the skin. YMMV
