After reading far too many of these "which is better, bullet X or bullet Y" posts, I have concluded that one should use a premium bullet and it does not matter much, if at all, which one.
I use 180 grain Partitions in .300, 450 grain TSXs in .458, and 450 grain North Fork solids (the best) for specialized situations.
These work. If I shoot something in the chest, there is no reason for a second shot. I can't see the slightest reason to experiment with something else.