Isn't it interesting folks have different takes. Of course when rimfire hunting, I don't care if they walk off or not. No big deal and I have the patience to get close enough or wait for the right shot.
OTOH if I HAVE to kill one for whatever reason, I'd probably at least use a 223 or 243 with a good bullet. If i had to take ANY shot presented, then I"d probably take even more gun.
Well said, Jeff, and spot on.