I hunt from VA to FL and have a few rifles already in my stable, but I'm looking for that one that I'll carry 90% of the time. I used to use 3-4 different rifles during the season and want that one that I get to know like the back of my hand. I do reload. My thoughts of rifles and calibers. I'm sure this has been done a million times on here. Shots from 25-400yds depending on the state. I have good glass to put on the rifle that I finally decide on. My initial thoughts....

Rifles:
Bergara B14
Christensen Mesa
Tikka T-3X

Caliber choices:
270
6.5 Creedmoor
7mm mag
* A 280 if I could find one in the right rifle.

It's ashame the rifle business for manufacturers has gone where it's gone. Id love a 338 Federal in a Tikka or a 358 Winchester in a Ruger Hawkeye 77 for a lot of my hunting under 300yds.