I’ve had a few of the .30 - .338 magnums. 340 Weatherby, 338 Win Mag, 300 Weatherby and the 300 Win Mag. Still have the 338 Win Mag. That gun with 210 Noslers just works. That bullet has taken 2 Grizzlies for me. No complaints. Also Elk and Deer. While certainly magnum recoil, I’d rather shoot it than the other 3. Jump up to 250’s and that changes. The Weatherby’s are brutal. I didn’t see a lot of difference between the 338 and the 300 Win Mag. All 4 are more than enough for all of America’s Big Game. I’ve never hunted Brown Bear but with the right bullets and proper shot placement, all would be well. My biggest Grizzly was a B&C Bear that squared out at 8’ 1”. One shot was all that was required.